![]() Basic earnings per share was HK$6.8 cents (1HFY2022: HK$14.2 cents). The net profit attributable to equity holders decreased by 50.0% YoY to HK$80.0 million. In 1HFY2023 (for the six months ended 30 September 2022), the company had revenue of HK$1,893.2mn, up 31.1% YoY. Negative impact by the Pandemic, 1HFY2023 net profit margin under pressure during the period, 69.1% came from medical business and 22.8% came from aesthetic medical and beauty and wellness services business, respectively. As at 30 September 2022, EC Healthcare had a total of 154 service points comprising 134 in Hong Kong, 4 in Macau and 16 in Mainland China with the total aggregate g.f.a increased by 24.1% YoY to 557,000 sq. ![]() Company adopt a multi-specialist brand strategy with over 40 brands spanning across service segment of medical, aesthetic medical and beauty and wellness (represent aesthetics medical, traditional beauty, haircare and ancillary wellness services and the sale of skincare, healthcare and beauty products). This may be limited to China, but as app stores receive more regulatory scrutiny worldwide, similar dynamics may eventually gain traction elsewhere (or even in new forms like cloud gaming via browsers or instant games).The principal activities of EC Healthcare is the provision of medical and healthcare services in Hong Kong, Macau and the Mainland China. ![]() In other words, the combination of video platform and games platform could grow more competitive - YouTube + Google Play, Bilibili + TapTap, TikTok + new Bytedance platform - and might ultimately make 0% revenue share the norm. The obvious name missing is Bytedance therefore, it wouldn’t be surprising to see Bytedance launch a self-developed gaming hub to counter TapTap with TikTok as its primary means of driving user acquisition. Tencent increased its position to 18% in 2020, Alibaba took a 10.8% stake back in 2019, and Sony bought in at $400M for 4.98% in 2020. Things get more interesting when you look at who owns a stake in Bilibili. It will fascinating to see how others follow suit. This powerful combo is already proven - miHoYo launched Genshin Impact in China primarily through a collaboration between Bilibili and TapTap, skipping the traditional Android app stores. XD’s Interim Report 2020 shows that TapTap’s advertising revenue sits at $38M, a 20% increase from the previous year.īack to X.D Networks’ investors: Bilibili’s investment signals a closer collaboration between China’s most popular long-form video network and China’s most popular gamer hub. Devs can now direct their Android user acquisition efforts towards TapTap, which creates a win-win-win situation: TapTap gets more users, the players get an amazing gamer hub, and devs don’t pay any store fees. While TapTap is available on both Android and iOS, only the Android version allows players to download games directly (the iOS version serves only as the community hub). While X.D Network has many successes as a game developer, its mobile game platform TapTap plays a more important role in China’s gaming ecosystem and is likely the key to investor interest.įor the uninitiated, TapTap is a community-focused mobile game platform that allows studios to distribute their games at 0% revenue share. Bilibili recently announced it will invest $123M for a 4.72% stake while Alibaba bought 0.76% for $20M. Shanghai-based X.D Network is in the center of the action, and the company just welcomed two new prominent investors to its roster. This is most striking in China, where developers are increasingly questioning the legacy app store distribution and business model. ![]() It’s clear that as anticompetitive pressures rise, content providers in certain regions are beginning to gain leverage in an evolving ecosystem with new models of user acquisition. There are major momentum shifts happening in mobile games distribution around the world: Apple vs Epic, app store fee reductions, Genshin Impact bypassing major Chinese app stores at launch, etc.
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![]() Centaur’s is an elegant thin line other versions are two-weighted.Ĭaps (hung)-To optically align, hang the diagonals of A, W, V, and Y and the arms of the T when using justified lines of caps.Ĭaps (regular)-Five to ten percent additional spacing often improves the color of a line of caps. Use half-word spacing around it.īrackets-Brackets can embrace an otherwise lonely folio. If a stop is needed between disparate bits of copy, a center dot of the same point size will do the trick in a more subdued manner. There are many examples of good text settings in books and magazines on typography.īullets-Unless you are selling used auto parts, or dumpsters, avoid using bullets heavier than the text they are distracting. Do not use headline faces for body copy: they were not designed for this purpose. Shifting the margins of the page has significant impact on the design.īody text-Avoid setting body text in all caps, or italics, or reversed out type. Negative space between words or paragraphs becomes an integral part of the design. Align figures on the decimal points.Īsymmetrical (contemporary format)-A layout in which the type relates more closely to the edge of the page than normal margins. In right-justified settings, periods, commas, and quotation marks should hang to the right. Ts, As, Vs, Ws and any letters with large amounts of negative space should hang to the left. ![]() If type is set flush left, punctuation such as quotation marks may hang in the margins. Better, specify a font complete with accents.Īlignment-See Centered, Flush left, Flush right, and Justified.Īlignment (optical)-Type should align visually, not mechanically. ![]() Lines of type must be leaded to accommodate them.Īccents (floating)-Floating accents are extremely difficult to place with small type size. Personal preference also plays a great part in typography.”Īccents (caps)-In the U.S. These are not my rules: they are common knowledge gleaned from reading about type, teaching, and using it. Doyald introduces this section, “The following list contains advice that will last a long time. ![]() If you still need help, select Contact Support to be routed to the best support option.Īdmins should view Help for OneDrive Admins, the OneDrive Tech Community or contact Microsoft 365 for business support. ![]() With this release, Microsoft expands on existing local storage and processing commitments, greatly reducing data flows out of Europe. If your country or region is not listed below, please visit the Microsoft store to see what products are available for you.įor more help with storage plans, see Storage plan subscription and billing questions.įixes or workarounds for recent issues in OneDrive Need more help?įor help with your Microsoft account and subscriptions, visit Account & Billing Help.įor technical support, go to Contact Microsoft Support, enter your problem and select Get Help. Beginning on January 1, 2023, Microsoft will offer customers the ability to store and process their customer data within the EU Data Boundary for Microsoft 365, Azure, Power Platform, and Dynamics 365 services. Note that if you already have a OneDrive subscription, you won't be able to see prices in different countries/regions. Note that if you already have a OneDrive subscription, you wont be able to see prices in different countries/regions. Note that no matter where customer data is stored, Microsoft does not control or limit the locations from which customers or their end users may access their data.Select the country/region for which you want to see the available storage plans. OneDrive storage plans by country/region OneDrive storage plans by country/region OneDrive (home or personal) Select the country/region for which you want to see the available storage plans.
![]() This has been brought up in numerous threads round the net. PC System Requirements, for some strange reason, seem a little on the high side. If you try to follow him Manny states he could just leave now but he has to fix things that the corrupt officials had been doing and refuses to leave. After speaking to him, he starts singing This Little Light again and heads off into the tunnel – it is very touching. His small story sees him circling round in a small pool of water to balance things out in his life. When you meet him at the train station, that is the last stop before the afterlife. As an example, near the start of Year 4 you will meet Chepito again, last seen working under water. The story is what keeps you playing through it there are some truly beautiful moments in this game. You can literally just use a guide for some of the trickier/obscure puzzles and play through it over a few days to completion. Overall Grim Fandango Remastered is still a fantastic game it has heart and has been lovingly restored by its original creators. Grim Fandango Remastered – Launch Trailer I would suggest enabling the commentary on a second play through and enjoy the game as is on a first play. There is also a director’s commentary that you can enable where the developers will chip in on virtually every screen talking about their memories of the initial creation and the remaster. Original voice work has been tidied up and the musical score has been redone with a live orchestra – the game has never sounded better, in all fairness, and they have definitely made the right decision in doing so. Personally I would stick with the 4:3 aspect ratio for the best experience. You also have the option of 16:9 Widescreen which just stretches the image due to original assets and story boards being 4:3, or you can play it with plain black bars down each side or what can be best described as a Noir-style banner instead of the black bars. You can, at the press of a button, switch to the classic models and lighting if you wish to experience the game the way it was when first released. Manny’s office, for example, at the start now casts shadows from the blinds across characters and the scene itself is a little more subdued. On top of that, most screens have new lighting that was not possible back in the day. The main difference here is the character models – they have tidied up all the textures, giving them a crisper/sharper look. Backgrounds are virtually the same as the original release – pre-rendered artwork that you interact with. I did notice a few of the shorter scenes did occasionally show artefacts but nothing major. Most cutscenes, albeit a little on the low resolution side, look so much better. This is the first thing that struck me from the off – Double Fine managed to get hold of the original source material so they were able to work on that tidying it up. Visually, there has been a lot of work done to remove artefacts from the cutscenes. They need to patch this so you can state what you are using so that buttons are marked out correctly. Personally, I played it start to finish with the pad my only gripe here though is that the buttons are marked as if using a Playstation Controller. Control-wise for the latter two you can use either the cursor keys or a gamepad. ![]() I do remember the original having the latter two control schemes so point-and-click is the new one here and fits the genre perfectly, if that is your thing. There is also the original tank controls (rotate left/right and forward to move) and there is also the camera-specific movement which, at times, can cause a little confusion if you stop to look at something and the next movement you make requires a different direction on the controller! The game has an all new point-and-click interface which makes me believe, if successful, that it will become available for IOS and Android as that can literally be converted to touch controls. ![]() So with the remaster what can you expect? ![]() The CineHub wireless unit ties the whole system together using WiSA (Wireless Speaker and Audio Association) technology. ![]() If you’ve got one extra wall socket, Enclave also sells a CineHome Duo PRO ($2,094) system, which is the same as the CineHome PRO but with a second subwoofer (CineHome PRO users can add a second Enclave subwoofer at any time if they wish). So you may not have to string speaker wires along your walls, but you will need several available power outlets. For wall mounting, there are keyholes in the back of each speaker except for the subwoofer, and the left and right rear speakers also have 1/4-inch threaded mount options in the back.Īltogether, the CineHome PRO system utilizes 11 Class-D digital amplifiers. The system’s subwoofer is appropriately bulky, measuring 18.8-inches high, 11.8-inches wide, and 14.4-inches deep and weighing 26.6 pounds to accommodate its 10-inch front-firing woofer. The smaller left and right vertically standing rear speakers are 16-inches-tall, 4.6-pound mini-towers, and have one 3-inch driver and one 1-inch tweeter inside. The 24-inch-wide, 7.3-pound center speaker also has two 3-inch drivers and a 1-inch tweeter it is basically the same design as the left and right front speakers except that it lies horizontally beneath your TV rather than standing vertically. The 24-inch-tall, 7.3-pound left and right front speakers are meant to stand vertically and each has two 3-inch drivers and a 1-inch tweeter inside. That big sound comes from a six-piece speaker system that does not skimp on size. The Enclave CineHome PRO ($1,599) promises a big surround sound experience from an easy-to-setup wireless 5.1 surround sound system. SEE IT The Enclave CineHome PRO wireless home theater system’s design Built on a 24-bit wireless audio standard and certified by THX for quality and consistency, this wireless home theater system offers considerable audio quality and performance while only requiring one HDMI cable from your TV. They also typically surround you with wires, however, because while Bluetooth surround sound systems seem convenient, most wireless 5.1 surround sound has unacceptable latency and a hard time keeping the sound synced to the video. A single soundbar and the latest immersive audio processing can offer a big step up, but the best surround sound systems still actually surround you with physical speakers. Built-in flatscreen TV speakers just don’t quite deliver. However, an ultrawide screen and microwave popcorn can’t make up for one vital part of the actual theater experience: the sound. The better that new QLED or OLED TV looks for less, the more the term “home theater” becomes literal. At the same time, first-run movies are now commonly available to stream. TVs are growing larger while getting cheaper. We may earn revenue from the products available on this page and participate in affiliate programs. If Naruto manages to pass this final test, he will become an official ninja. The day of the all-important Ninja Academy graduation exam is at hand. During 2009, Viz released two other DVD boxes containing episodes 1-25 and 26-52, respectively. In North America episodes from this season were released on nine DVD compilations by Viz Media between Maand February 20, 2007, with two compilations of thirteen and twelve episodes released for the first season, the first of these compilations was nominated at the American Anime Awards for best package design. A total of twelve volumes were released by Sony Pictures Entertainment in 2003 from January 1 to December 3. In Japan the season was collected in both VHS and DVD format. It aired on Cartoon Network's Toonami and YTV's Bionix programming blocks. The English airing of the first season was from September 2005 to May 2006. The first season ran from October 2002 to May 2003 in Japan on TV Tokyo. He is assigned to Team 7, a three-person cell that has to complete missions for the village. They are based on the Naruto manga series by Masashi Kishimoto The series follows the young teenager Naruto Uzumaki who wants to become the Hokage, the leader of the ninja village where he lives, in order to become a respectable ninja. The episodes were released in North America by Viz Media and on Europe and South America by Warner Bros. It’s not a choice an artist would make, but Zaslav isn’t an artist.The first season of the Naruto anime series. It motivates Cartoon Network to sell the '90s nostalgia that a lot of millennial viewers are looking for, but it means we might get less creative programming. As far as a business decision goes, Zaslav is making a safe bet when making TV for an audience that already exists. Recent years have proven that viewers prefer shows that seem nostalgic and give them new spins on old shows that they loved as kids. The point is that these animation companies will shift to making more familiar TV shows. For example, there is already a new Powerpuff Girls reboot scheduled to be made. ![]() It’s quite possible that Cartoon Network Studios would work on fewer original shows and might shift more towards reboots and remakes of old shows. Animation probably won’t experience that much of a change, viewers might see differing content from Cartoon Network. Animation typically keeps making shows that stay within the spheres of things like DC and Mortal Kombat. ![]() Related: Best Cartoon Network Shows of the 2000s, RankedĬartoon Network is largely known for producing original TV shows, creating shows like Over the Garden Wall, Stephen Universe, and Adventure Time. Cartoon Network responded to the Twitter rumors by posting its own tweets saying things like “Y’all we’re not dead, just turning 30,” and reaction memes like the following: Under the new setup, a kids and family series development team will be led by Audrey Diehl, adult animation development will be led by Peter Girardi, and animated longform series development will be led by Sammy Perlmutter, with Bobbie Page leading main production.īut aside from these executive developments, things will remain largely the same for viewers. They’ll be relying on the same studio for their animation needs.Īlthough this employment shake-up does come with a change in leadership, Variety reports: ![]() That is to say, there will be no changes to the actual Cartoon Network or WB platforms. But now, the two artistic studios will become one, producing content for their separate channels. The companies had already shared the same programming, casting, legal, and artist relations teams, so there was already cooperation between the two. Animation will still work for their own respective stations. Cartoon Network Studios will still produce animation for Cartoon Network, Adult Swim, and HBO Max, and Warner Bros. ![]() I was either the hero of the sidekicks or the sidekick to the heroes." The film was released on July 29, 2005, receiving favorable reviews, and budgeted at US$35 million, it grossed US$63.9 million domestically. Winstead said of her role, "I bounced around. 2005–2011 įollowing a minor role in the indie comedy Checking Out (2005), she took on a larger role as a school senior turned the main antagonist in the Walt Disney Pictures film Sky High, about an airborne school for teenage superheroes. She was offered a role in the film A Cinderella Story, but turned it down as she had just graduated from school and was going on a cruise with friends (where she met Riley Stearns, her future husband). In 2004, Winstead played a supporting role in MTV's made-for-television film Monster Island. The series was canceled after ten episodes. Winstead's next significant television role was in the short-lived CBS drama series Wolf Lake (2001–02), as the daughter of Tim Matheson's character. She left to pursue other interests, later stating, "I really had one of the smallest roles on Passions, so I didn't get too involved. She gained her first major role as Jessica Bennett in the NBC soap opera Passions, from 1999 to 2000. After her brief performance in that show, Winstead began making appearances in various television series and earned guest roles in Touched by an Angel and Promised Land. Winstead appeared in a production of Joseph and the Amazing Technicolor Dreamcoat starring Donny Osmond. As she was still a teenager at the time, this required her to be homeschooled through most of high school. You know, your body has to stay that way for your entire life, and it's pretty hard on your muscles and your bones." Realizing a dance career was unlikely, she turned to acting. She later said, "I realized pretty early on that I was already too tall by the time I was 13. As she entered her teens, she was forced to quit ballet due to her height. During her youth, she hoped to pursue a career as a ballerina and appeared in local ballet productions. She studied dance in a Joffrey Ballet summer program in Chicago and sang in the International Children's Choir. When she was five years old, her family moved to Sandy, Utah, where she attended Peruvian Park Elementary and took advanced classes. Her grandfather, Ambler William Winstead, was a cousin of actress Ava Gardner. Mary Elizabeth Winstead was born on November 28, 1984, in Rocky Mount, North Carolina, to Betty Lou (née Knight) and James Ronald Winstead and is the youngest of five children. Since 2013, Winstead has performed as music duo Got a Girl with Dan the Automator. Her other roles include the comedy drama All About Nina (2018), the action thriller film Gemini Man (2019), and as the Huntress in Birds of Prey (2020). She reprised her role as Lucy Gennero-McClane in A Good Day to Die Hard (2013) and returned to television with roles in the supernatural drama series The Returned (2015), the political satire science fiction comedy series BrainDead (2016), the period medical drama series Mercy Street (2016–17) and the black comedy crime drama anthology series Fargo (2017). Winstead continued her Scream Queen roles in the sci-fi horror film The Thing (2011), as Mary Todd Lincoln in the fantasy horror film Abraham Lincoln: Vampire Hunter (2012), and in the psychological horror thriller film 10 Cloverfield Lane (2016). ![]() Her critically acclaimed performance as an alcoholic struggling with sobriety in the Sundance drama Smashed (2012) was followed by a series of roles in other well-received independent films, including The Beauty Inside (2012), The Spectacular Now (2013), Faults (2014), Alex of Venice (2014), and Swiss Army Man (2016). She came to wider attention for her roles in the horror series Wolf Lake (2001–2002), the giant monster film Monster Island (2004), the supernatural horror film Final Destination 3 (2006), the slasher film Black Christmas (2006), and the exploitation horror film Death Proof (2007).įurther success came with her roles as John McClane's daughter Lucy Gennero-McClane in Live Free or Die Hard (2007) and Ramona Flowers in Scott Pilgrim vs. ![]() She went on to appear in series such as Tru Calling (2004) and films including the superhero film Sky High (2005). ![]() Her first significant role was that of Jessica Bennett on the NBC soap opera Passions (1999–2000). Mary Elizabeth Winstead (born November 28, 1984) is an American actress and singer. The bars at the bottom left of the plot indicate the number of genes identified in each library (as shown in Subfigure A and B). C Upset plot showing the coordinance of genes identified in each library. Standard deviation of the mean at each subsample point was also plotted but is not visible at this scale. Each line indicates the mean of 100 repeated subsamples for each integer percentage of the overall number of reads in that library. B Saturation analysis of the number of unique genes identified in each library. The right plot zooms into the “other” (orange) biotypes from the left plot. A Comparison of the number of unique genes identified (having 1 or more reads mapped) and their biotypes in each library. Unselected libraries capture slightly less complex transcriptomes due to their reduced read depth. The omission of poly(A) selection minimizes poly(A)-tail-derived biases and allows for a substantial reduction of input sample RNA, enhancing the accuracy and expanding the applications of dRNA-seq. We extend our analyses to include samples from another lab to show that poly(A) selection introduces undue noise in published data. Here, by analyzing libraries with and without poly(A) selection, we show that the use of oligo (dT)-based poly(A) selection introduces bias and variability attributable to mRNA poly(A) tail differences. An ideal dRNA-seq protocol would explicitly avoid biases inherent in poly(A) selection. Work from several groups highlights examples where poly(A)-tail lengths and deadenylation rates differ between mRNAs according to their age or gene-of-origin. In other sequencing applications, poly(A) selection artificially enriches for longer tailed RNA species and therefore would be expected to also bias the dRNA-seq technique. With the recent introduction of total RNA as input for ONT’s dRNA-seq protocol, the opportunity to avoid additional handling by omitting poly(A) selection has increased the utility of the technique, and provides the opportunity to directly answer questions regarding the potential biases introduced by the previous standard of oligo (dT)-based selection methods. ![]() Among transcriptomic techniques, the Oxford Nanopore Technologies (ONT) direct RNA-sequencing (dRNA-seq) platform stands out by avoiding nearly all of these steps, and a prior study detected less bias in Oxford’s dRNA-seq protocol compared to several others. These biases can arise at a number of steps, including: RNA fragmentation, reverse transcription priming, PCR amplification, and capture on the sequencing platform. Indeed, comparison of several RNA-seq techniques on identical samples demonstrates biases from each protocol. But before RNAs can be sequenced, they must first be captured in a manner amenable to sequencing.īiases inherent in RNA capture protocols can skew the view of the transcriptome (reviewed in ). Several techniques of genome-wide RNA sequencing (RNA-seq) exist to survey the transcriptome, broadly falling into sequencing-by-synthesis (Illumina, 454, PacBio) or sequencing-by-current (Oxford Nanopore). Identification of RNAs in a biological sample is central to diverse research applications including mechanistic studies, diagnostics, and high-dimensional phenotyping. Our work expands the utility of direct RNA-seq by validating the use of total RNA as input, and demonstrates important technical artifacts from poly(A) selection that inconsistently skew mRNA expression and poly(A) tail length measurements. Importantly, we show poly(A) selection is dispensable for Oxford Nanopore’s direct RNA-seq technique, and demonstrate successful library construction without poly(A) selection, with decreased input, and without loss of quality. Interestingly, we identify a population of mRNAs (> 10% of genes’ mRNAs) that are inconsistently captured by poly(A) selection due to highly variable poly(A) tails, and demonstrate this phenomenon in our hands and in published data. As expected, poly(A) selection skews sequenced mRNAs toward longer poly(A) tail lengths. Here, we show that poly(A) selection biases Oxford Nanopore direct RNA sequencing. In many applications it is well-known that poly(A) selection biases the view of the transcriptome by selecting for longer tailed mRNA species. RNA-seq users often first enrich for mRNA, with the most popular enrichment method being poly(A) selection. Genome-wide RNA-sequencing technologies are increasingly critical to a wide variety of diagnostic and research applications. ![]() Reviews are not monitored for bug reports, please use GitHub for issues and feature requests. The extension is also available for Edge and Safari: Alternatively, you can download the Google App, which includes Google Lens, their image recognition technology. You can use the phone’s web browser (For example, Safari), go to Google Images. Visit the extension's privacy policy for more information. There are two ways of making Google reverse image searches from Apple smartphones. The image you select during a search is sent to the requested service, such as Bing Images. Visit the chrome://extensions page and open the extension's details to find the option. The "Allow access to file URLs" option must be enabled for the extension to search with local images opened in a tab. ![]() Pasting images from the clipboard is also supported. Browse: search with an image from your device.Capture: search with a captured area of the page.This search mode is preferred for sites which do not allow the direct linking of images, such as private sites. Select image: select an image on the page and search with the image file.Select URL: select an image on the page and search with the image URL.The search mode can be set independently for the context menu and the browser toolbar from the extension's options. The extension also supports searching with images from your device, images from private sites, and captured areas of the page.Ī handful of search modes are offered that serve different use cases. Images positioned at the selected area are detected regardless of how they were embedded in the page. Visit the wiki for the full list of supported search engines. The extension enables you to search for images from the context menu and the browser toolbar with the help of a diverse set of reverse image search engines, which can be toggled and reordered from the extension's options. Search by Image is also popular among photographers, helping artists explore how their work is shared on the web, while shoppers find it valuable for discovering similar products at discounted prices. The extension helps journalists and researchers verify the authenticity of images, and assists in the identification of false information on social media. If you'd like to support the continued development of the extension, please check out Search by Image is an open source project made possible thanks to a community of awesome supporters. Search by Image is a browser extension that makes effortless reverse image searches possible, and comes with support for more than 30 search engines. A powerful reverse image search tool, with support for various search engines, such as Google, Bing, Yandex, Baidu and TinEye. |
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